Systems Integration Engineer II
Company: Freenome
Location: Brisbane
Posted on: January 27, 2026
|
|
|
Job Description:
Freenome is hiring a Systems Integration Engineer to participate
in a cross-functional team and contribute to the development of
next generation NGS assays/products for early cancer detection. You
will work in a Product Development team of world-class Scientists
and Engineers focused on delivering Freenome’s IVD assay portfolio.
If you are passionate about deploying the power of NGS-based
diagnostics in clinical care, and take pride in providing technical
expertise to a growing team of Systems Integration Engineers,
making a significant individual impact, we would love to speak with
you! As part of a dynamic, flexible company you will be adapting to
rapid technological progress and change, and help the team building
the platform do the same. The role reports to the Senior Manager,
Development & Scientific Operations. This role will be an onsite
role based in our Brisbane, California headquarters. What you’ll
do: Execute end-to-end assay workflows using industry-leading
automation platforms to support development of Freenome’s next
generation diagnostic products. Hands-on design and execution of
complex test methods to assess hardware and system performance per
Design Input Requirements. Evaluate resulting system performance,
speed and throughput, and identify root causes for system-level
issues and failures. Contribute to dFMEA, pFMEA, risk management,
hazard assessment, and design review sessions with Engineering,
Automation, and Systems Integration teams. Analyze outputs and
identify HW, FW, and SW mitigating solutions to implement adequate
risk control measures. Identify and steward Systems Integration
initiatives to enable achievement of critical path project
milestones/timelines. Support the system evaluation process through
development and execution of system level test plans and protocols,
including data analysis, interpretation and communication of
results and their impact through written reports, design reviews,
and interactive discussions. Apply sophisticated analytical problem
solving skills to reagent and system integration issues to identify
critical performance factors for assay development. Apply broad
scientific, technical or professional concepts in accordance with
area(s) objectives. Assess results for applicability, validity, and
conformance to Product Requirements. Write and manage requirements
as part of Project Team. Create and maintain design documentation
in Design History Files. Must haves: Bachelor’s degree or Master’s
degree with 2 years of relevant work experience OR Doctoral degree.
Education or equivalent experience in a relevant field such as
Biology, Biochemistry, Bioengineering, Biomedical Engineering, etc.
Previous experience as a hands-on engineer, scientist, or product
developer (e.g. System Integration Scientist / Engineer, System
Development Scientist / Engineer, or related occupation).
Experience with developing and integrating complex instrumentation
systems which incorporate optical, mechanical, thermal, and
firmware components. Data analysis expertise and experience with
various data analysis software packages. Well-developed
mathematical and statistical analysis skills. (i.e., JMP, R, DOE).
Knowledge of SQL, Python, R or other programming languages highly
desired. Knowledge of a broad range of principles of biology,
chemistry and physics, such as spectroscopic techniques, organic
chemistry, electromagnetic theory, and thermodynamics. Strong
integration analytical, process validation and troubleshooting
skills to understand system interfaces and be able to quickly
analyze, troubleshoot, and resolve system interoperability
problems. Working knowledge of design of experiments,
interpretation of test results, failure investigation and root
cause failure analysis. Excellent communication skills, verbal and
written. Demonstrated ability to understand and comply with
applicable FDA regulations and company operating procedures,
processes, policies and tasks. Work as part of a team to guarantee
high quality of technical and design control documentation in
alignment with Freenome’s Quality requirements. Benefits and
additional information: The US target range of our base
salary/hourly rate for new hires is $100,725 - $140,700 . You will
also be eligible to receive pre-IPO equity, cash bonuses, and a
full range of medical, financial, and other benefits depending on
the position offered. Please note that individual total
compensation for this position will be determined at the Company’s
sole discretion and may vary based on several factors, including
but not limited to, location, skill level, years and depth of
relevant experience, and education. Freenome is proud to be an
equal-opportunity employer, and we value diversity. Freenome does
not discriminate on the basis of race, color, religion, marital
status, age, national origin, ancestry, physical or mental
disability, medical condition, pregnancy, genetic information,
gender, sexual orientation, gender identity or expression, veteran
status, or any other status protected under federal, state, or
local law.
Keywords: Freenome, Sacramento , Systems Integration Engineer II, Engineering , Brisbane, California
